Frontotemporal dementia is a spectrum of different disease. They are broadly characterised by shrinkage, or atrophy of brain regions such as the frontal lobe and the frontal sections of the temporal lobe.
The symptoms range from changes in personality and behaviour with frontal lobe damage, as well as higher cognitive skills such as planning and judgment. With damage to the temporal love, there’s often problems with speech production and language.
Of all the conditions that cause dementia, frontotemporal dementia has the strongest genetic predisposition with 30-40% of cases linked to particular genetic mutations and because of this genetic disposition these cases tend to have a relatively early onset.
Behavioural variant frontotemporal dementia– frontal lobe damage and involves a change in personality of the development of behavioural symptoms.
Primary progressive aphasias (PPA) are due to damage to the temporal lobe which result in problems with language and speech.. A number of different types of language impairment are different forms of PPA including semantic dementia, primary non-fluent aphasia (PNFA) and logopenic aphasias.